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Genomic Deoxyxylulose Phosphate Reductoisomerase (DXR) Mutations Conferring Resistance to the Antimalarial Drug Fosmidomycin in E. coli
Sequence to activity mapping technologies are rapidly developing, enabling the generation and isolation of mutations conferring novel phenotypes. Here we used the CRISPR EnAbled Trackable genome Engineering (CREATE) technology to investigate the inhibition of the essential ispC gene in its native ge...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | ACS Synth Biol |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6928208/ https://ncbi.nlm.nih.gov/pubmed/30462485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.8b00219 |
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