Genomic Deoxyxylulose Phosphate Reductoisomerase (DXR) Mutations Conferring Resistance to the Antimalarial Drug Fosmidomycin in E. coli

Sequence to activity mapping technologies are rapidly developing, enabling the generation and isolation of mutations conferring novel phenotypes. Here we used the CRISPR EnAbled Trackable genome Engineering (CREATE) technology to investigate the inhibition of the essential ispC gene in its native ge...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Synth Biol
Main Authors: Pines, Gur, Oh, Eun Joong, Bassalo, Marcelo C., Choudhury, Alaksh, Garst, Andrew D., Fankhauser, Reilly G., Eckert, Carrie A., Gill, Ryan T.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928208/
https://ncbi.nlm.nih.gov/pubmed/30462485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.8b00219
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki