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Functional genetic analysis of the Plasmodium falciparum deoxyxylulose 5-phosphate reductoisomerase gene

Novel antimalarial drugs are urgently needed to treat severe malaria caused by Plasmodium falciparum. Isoprenoid biosynthesis is a promising target pathway, since the biosynthetic route in Plasmodia is biochemically distinct from the mevalonate pathway in humans. The small molecule fosmidomycin is a...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Odom, Audrey R., Van Voorhis, Wesley C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814890/
https://ncbi.nlm.nih.gov/pubmed/20018214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2009.12.001
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