ADAM10 sheddase activation is controlled by cell membrane asymmetry

Dysregulation of the disintegrin-metalloproteinase ADAM10 may contribute to the development of diseases including tumorigenesis and Alzheimer’s disease. The mechanisms underlying ADAM10 sheddase activation are incompletely understood. Here, we show that transient exposure of the negatively charged p...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Cell Biol
Egile Nagusiak: Bleibaum, Florian, Sommer, Anselm, Veit, Martin, Rabe, Björn, Andrä, Jörg, Kunzelmann, Karl, Nehls, Christian, Correa, Wilmar, Gutsmann, Thomas, Grötzinger, Joachim, Bhakdi, Sucharit, Reiss, Karina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927242/
https://ncbi.nlm.nih.gov/pubmed/30753537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz008
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