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Role of ADAM10 and ADAM17 in Regulating CD137 Function

Human CD137 (4-1BB), a member of the TNF receptor family, and its ligand CD137L (4-1BBL), are expressed on immune cells and tumor cells. CD137/CD137L interaction mediates bidirectional cellular responses of potential relevance in inflammatory diseases, autoimmunity and oncology. A soluble form of CD...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Seidel, Jana, Leitzke, Sinje, Ahrens, Björn, Sperrhacke, Maria, Bhakdi, Sucharit, Reiss, Karina
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962946/
https://ncbi.nlm.nih.gov/pubmed/33800462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052730
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