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ADAM10 sheddase activation is controlled by cell membrane asymmetry
Dysregulation of the disintegrin-metalloproteinase ADAM10 may contribute to the development of diseases including tumorigenesis and Alzheimer’s disease. The mechanisms underlying ADAM10 sheddase activation are incompletely understood. Here, we show that transient exposure of the negatively charged p...
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| Gepubliceerd in: | J Mol Cell Biol |
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| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6927242/ https://ncbi.nlm.nih.gov/pubmed/30753537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz008 |
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