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Intramolecular interaction in LGN, an adaptor protein that regulates mitotic spindle orientation
Proper mitotic spindle orientation requires that astral microtubules are connected to the cell cortex by the microtubule-binding protein NuMA, which is recruited from the cytoplasm. Cortical recruitment of NuMA is at least partially mediated via direct binding to the adaptor protein LGN. LGN normall...
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| 發表在: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6926459/ https://ncbi.nlm.nih.gov/pubmed/31732560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011457 |
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