A Conserved Region between the TPR and Activation Domains of p67(phox) Participates in Activation of the Phagocyte NADPH Oxidase

The phagocyte NADPH oxidase, dormant in resting cells, is activated during phagocytosis to produce superoxide, a precursor of microbicidal oxidants. The membrane-integrated protein gp91(phox) serves as the catalytic core, because it contains a complete electron-transporting apparatus from NADPH to m...

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Detalhes bibliográficos
Main Authors: Maehara, Yuichi, Miyano, Kei, Yuzawa, Satoru, Akimoto, Risa, Takeya, Ryu, Sumimoto, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951218/
https://ncbi.nlm.nih.gov/pubmed/20679349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.161166
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