Phosphorylation of p47(phox) directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation

Protein–phosphoinositide interaction participates in targeting proteins to membranes where they function correctly and is often modulated by phosphorylation of lipids. Here we show that protein phosphorylation of p47(phox), a cytoplasmic activator of the microbicidal phagocyte oxidase (phox), elicit...

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Detalhes bibliográficos
Main Authors: Ago, Tetsuro, Kuribayashi, Futoshi, Hiroaki, Hidekazu, Takeya, Ryu, Ito, Takashi, Kohda, Daisuke, Sumimoto, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153580/
https://ncbi.nlm.nih.gov/pubmed/12672956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0735712100
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