Phosphorylation of p47(phox) directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation

Protein–phosphoinositide interaction participates in targeting proteins to membranes where they function correctly and is often modulated by phosphorylation of lipids. Here we show that protein phosphorylation of p47(phox), a cytoplasmic activator of the microbicidal phagocyte oxidase (phox), elicit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ago, Tetsuro, Kuribayashi, Futoshi, Hiroaki, Hidekazu, Takeya, Ryu, Ito, Takashi, Kohda, Daisuke, Sumimoto, Hideki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2003
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC153580/
https://ncbi.nlm.nih.gov/pubmed/12672956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0735712100
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