Phosphorylation of p47(phox) directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation
Protein–phosphoinositide interaction participates in targeting proteins to membranes where they function correctly and is often modulated by phosphorylation of lipids. Here we show that protein phosphorylation of p47(phox), a cytoplasmic activator of the microbicidal phagocyte oxidase (phox), elicit...
محفوظ في:
| الحاوية / القاعدة: | Proc Natl Acad Sci U S A |
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| المؤلفون الرئيسيون: | , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
National Academy of Sciences
2003
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153580/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12672956/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0735712100 |
| الوسوم: |
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