Intramolecular interaction in LGN, an adaptor protein that regulates mitotic spindle orientation

Proper mitotic spindle orientation requires that astral microtubules are connected to the cell cortex by the microtubule-binding protein NuMA, which is recruited from the cytoplasm. Cortical recruitment of NuMA is at least partially mediated via direct binding to the adaptor protein LGN. LGN normall...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Takayanagi, Hiroki, Hayase, Junya, Kamakura, Sachiko, Miyano, Kei, Chishiki, Kanako, Yuzawa, Satoru, Sumimoto, Hideki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2019
Pynciau:
Cell Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926459/
https://ncbi.nlm.nih.gov/pubmed/31732560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011457
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