Automated tracking of mitotic spindle pole positions shows that LGN is required for spindle rotation but not orientation maintenance

Spindle orientation defines the plane of cell division and, thereby, the spatial position of all daughter cells. Here, we develop a live cell microscopy-based methodology to extract spindle movements in human epithelial cell lines and study how spindles are brought to a pre-defined orientation. We s...

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Bibliografiske detaljer
Main Authors: Corrigan, Adam M, Shrestha, Roshan L, Zulkipli, Ihsan, Hiroi, Noriko, Liu, Yingjun, Tamura, Naoka, Yang, Bing, Patel, Jessica, Funahashi, Akira, Donald, Athene, Draviam, Viji M
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865054/
https://ncbi.nlm.nih.gov/pubmed/23907121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25671
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