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Spindle rotation in human cells is reliant on a MARK2-mediated equatorial spindle-centering mechanism

The plane of cell division is defined by the final position of the mitotic spindle. The spindle is pulled and rotated to the correct position by cortical dynein. However, it is unclear how the spindle’s rotational center is maintained and what the consequences of an equatorially off centered spindle...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Main Authors: Zulkipli, Ihsan, Clark, Joanna, Hart, Madeleine, Shrestha, Roshan L., Gul, Parveen, Dang, David, Kasichiwin, Tami, Kujawiak, Izabela, Sastry, Nishanth, Draviam, Viji M.
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122980/
https://ncbi.nlm.nih.gov/pubmed/29941476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201804166
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