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Modeling of Noisy Spindle Dynamics Reveals Separable Contributions to Achieving Correct Orientation

The mechanisms by which the mammalian mitotic spindle is guided to a predefined orientation through microtubule-cortex interactions have recently received considerable interest, but there has been no dynamic model that describes spindle movements toward the preferred axis in human cells. Here, we de...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Corrigan, Adam M., Shrestha, Roshan, Draviam, Viji M., Donald, Athene M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601064/
https://ncbi.nlm.nih.gov/pubmed/26445440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.014
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