Spindle rotation in human cells is reliant on a MARK2-mediated equatorial spindle-centering mechanism

The plane of cell division is defined by the final position of the mitotic spindle. The spindle is pulled and rotated to the correct position by cortical dynein. However, it is unclear how the spindle’s rotational center is maintained and what the consequences of an equatorially off centered spindle...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Biol
Egile Nagusiak: Zulkipli, Ihsan, Clark, Joanna, Hart, Madeleine, Shrestha, Roshan L., Gul, Parveen, Dang, David, Kasichiwin, Tami, Kujawiak, Izabela, Sastry, Nishanth, Draviam, Viji M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2018
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122980/
https://ncbi.nlm.nih.gov/pubmed/29941476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201804166
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