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Structural basis for the recognition of the scaffold protein Frmpd4/Preso1 by the TPR domain of the adaptor protein LGN

The adaptor protein LGN interacts via the N-terminal domain comprising eight tetratricopeptide-repeat (TPR) motifs with its partner proteins mInsc, NuMA, Frmpd1 and Frmpd4 in a mutually exclusive manner. Here, the crystal structure of the LGN TPR domain in complex with human Frmpd4 is described at 1...

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Veröffentlicht in:Acta Crystallogr F Struct Biol Commun
Hauptverfasser: Takayanagi, Hiroki, Yuzawa, Satoru, Sumimoto, Hideki
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321472/
https://ncbi.nlm.nih.gov/pubmed/25664792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14028143
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