Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors

Understanding HIV-1 persistence despite antiretroviral therapy (ART) is of paramount importance. Both single-genome sequencing (SGS) and integration site analysis (ISA) provide useful information regarding the structure of persistent HIV DNA populations; however, until recently, there was no way to...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Patro, Sean C., Brandt, Leah D., Bale, Michael J., Halvas, Elias K., Joseph, Kevin W., Shao, Wei, Wu, Xiaolin, Guo, Shuang, Murrell, Ben, Wiegand, Ann, Spindler, Jonathan, Raley, Castle, Hautman, Christopher, Sobolewski, Michele, Fennessey, Christine M., Hu, Wei-Shau, Luke, Brian, Hasson, Jenna M., Niyongabo, Aurelie, Capoferri, Adam A., Keele, Brandon F., Milush, Jeff, Hoh, Rebecca, Deeks, Steven G., Maldarelli, Frank, Hughes, Stephen H., Coffin, John M., Rausch, Jason W., Mellors, John W., Kearney, Mary F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2019
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925994/
https://ncbi.nlm.nih.gov/pubmed/31776247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910334116
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