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Asymmetric Redox-Neutral Radical Cyclization Catalyzed by Flavin-Dependent ‘Ene’-Reductases

Flavin-dependent ‘ene’-reductases (EREDs) are exquisite catalysts for effecting stereoselective reductions. While these reactions typically proceed through a hydride transfer mechanism, we recently found that EREDs can also catalyze reductive dehalogenations and cyclizations via single electron tran...

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Detalhes bibliográficos
Publicado no:Nat Chem
Main Authors: Black, Michael J., Biegasiewicz, Kyle F., Meichan, Andrew J., Oblinsky, Daniel G., Kudisch, Bryan, Scholes, Gregory D., Hyster, Todd K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925616/
https://ncbi.nlm.nih.gov/pubmed/31792387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-019-0370-2
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