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Chondroitinase ABC reduces dopaminergic nigral cell death and striatal terminal loss in a 6-hydroxydopamine partial lesion mouse model of Parkinson’s disease
BACKGROUND: Parkinson’s disease (PD) is characterised by dopaminergic cell loss within the substantia nigra pars compacta (SNc) that leads to reduced striatal dopamine content and resulting motor deficits. Identifying new strategies to protect these cells from degeneration and retain striatal dopami...
Shranjeno v:
| izdano v: | BMC Neurosci |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6923832/ https://ncbi.nlm.nih.gov/pubmed/31862005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-019-0543-3 |
| Oznake: |
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