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Application of the Physical Disector Principle for Quantification of Dopaminergic Neuronal Loss in a Rat 6-Hydroxydopamine Nigral Lesion Model of Parkinson's Disease

Stereological analysis is the optimal tool for quantitative assessment of brain morphological and cellular changes induced by neurotoxic lesions or treatment interventions. Stereological methods based on random sampling techniques yield unbiased estimates of particle counts within a defined volume,...

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Detalhes bibliográficos
Publicado no:Front Neuroanat
Main Authors: Fabricius, Katrine, Barkholt, Pernille, Jelsing, Jacob, Hansen, Henrik H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727600/
https://ncbi.nlm.nih.gov/pubmed/29276478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2017.00109
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