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Chondroitinase ABC reduces dopaminergic nigral cell death and striatal terminal loss in a 6-hydroxydopamine partial lesion mouse model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is characterised by dopaminergic cell loss within the substantia nigra pars compacta (SNc) that leads to reduced striatal dopamine content and resulting motor deficits. Identifying new strategies to protect these cells from degeneration and retain striatal dopami...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Fletcher, Edward J. R., Moon, Lawrence D. F., Duty, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923832/
https://ncbi.nlm.nih.gov/pubmed/31862005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-019-0543-3
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