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Curcumin protects nigral dopaminergic neurons by iron-chelation in the 6-hydroxydopamine rat model of Parkinson’s disease

OBJECTIVE: Curcumin is a plant polyphenolic compound and a major component of spice turmeric (Curcuma longa). It has been reported to possess free radical-scavenging, iron-chelating, and anti-inflammatory properties in different tissues. Our previous study showed that curcumin protects MES23.5 dopam...

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Détails bibliographiques
Publié dans:Neurosci Bull
Auteurs principaux: Du, Xi-Xun, Xu, Hua-Min, Jiang, Hong, Song, Ning, Wang, Jun, Xie, Jun-Xia
Format: Artigo
Langue:Inglês
Publié: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560326/
https://ncbi.nlm.nih.gov/pubmed/22622825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-012-1238-2
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