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A direct heterotypic interaction between the DIX domains of Dishevelled and Axin mediates signaling to β-catenin
The Wnt-β-catenin signaling pathway regulates embryonic development and tissue homeostasis throughout the animal kingdom. Signaling through this pathway crucially depends on the opposing activities of two cytoplasmic multiprotein complexes: the Axin destruction complex, which destabilizes the downst...
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| Veröffentlicht in: | Sci Signal |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6923138/ https://ncbi.nlm.nih.gov/pubmed/31822591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaw5505 |
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