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A direct heterotypic interaction between the DIX domains of Dishevelled and Axin mediates signaling to β-catenin

The Wnt-β-catenin signaling pathway regulates embryonic development and tissue homeostasis throughout the animal kingdom. Signaling through this pathway crucially depends on the opposing activities of two cytoplasmic multiprotein complexes: the Axin destruction complex, which destabilizes the downst...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Yamanishi, Kumpei, Fiedler, Marc, Terawaki, Shin-ichi, Higuchi, Yoshiki, Bienz, Mariann, Shibata, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923138/
https://ncbi.nlm.nih.gov/pubmed/31822591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaw5505
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