Crystallization and preliminary X-ray crystallographic studies of the axin DIX domain

Axin is a negative regulator of the canonical Wnt signalling pathway that mediates the phosphorylation of β-catenin by glycogen synthase kinase 3β. The DIX domain of rat axin, which is important for its homooligomerization and interactions with other regulators in the Wnt pathway, was purified and c...

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Autores principales: Shibata, Naoki, Tomimoto, Yusuke, Hanamura, Toru, Yamamoto, Ryo, Ueda, Mai, Ueda, Yasufumi, Mizuno, Nobuhiro, Ogata, Hideaki, Komori, Hirofumi, Shomura, Yasuhito, Kataoka, Michihiko, Shimizu, Sakayu, Kondo, Jun, Yamamoto, Hideki, Kikuchi, Akira, Higuchi, Yoshiki
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2007
Materias:
Crystallization Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335085/
https://ncbi.nlm.nih.gov/pubmed/17554179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107022579
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