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Crystallographic characterization of the DIX domain of the Wnt signalling positive regulator Ccd1
Coiled-coil DIX1 (Ccd1) is a positive regulator that activates the canonical Wnt signalling pathway by inhibiting the degradation of the key signal transducer β-catenin. The C-terminal DIX domain of Ccd1 plays an important role in the regulation of signal transduction through homo-oligomerization a...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
International Union of Crystallography
2011
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3144790/ https://ncbi.nlm.nih.gov/pubmed/21795788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111016526 |
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