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Crystallographic characterization of the DIX domain of the Wnt signalling positive regulator Ccd1
Coiled-coil DIX1 (Ccd1) is a positive regulator that activates the canonical Wnt signalling pathway by inhibiting the degradation of the key signal transducer β-catenin. The C-terminal DIX domain of Ccd1 plays an important role in the regulation of signal transduction through homo-oligomerization a...
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| Main Authors: | , , , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
International Union of Crystallography
2011
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3144790/ https://ncbi.nlm.nih.gov/pubmed/21795788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111016526 |
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