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Semi-synthesis of ubiquitinated histone H2B with a native or non-hydrolyzable linkage

Post-translational modifications of histone proteins regulate all biological processes requiring access to DNA. Monoubiquitination of histone H2B is a mark of actively transcribed genes in all eukaryotes that also plays a role in DNA replication and repair. Solution and structural studies of the mec...

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Publicat a:Methods Enzymol
Autors principals: Morgan, Michael, Jbara, Muhammad, Brik, Ashraf, Wolberger, Cynthia
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917205/
https://ncbi.nlm.nih.gov/pubmed/30850047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.01.003
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