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Activation and regulation of H2B-Ubiquitin-dependent histone methyltransferases

Covalent modifications of histone proteins regulate a wide variety of cellular processes. Methylation of histone H3K79 and H3K4 is associated with active transcription and is catalyzed by Dot1L and Set1, respectively. Both Dot1L and Set1 are activated by prior ubiquitination of histone H2B on K120 i...

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Bibliografische gegevens
Gepubliceerd in:Curr Opin Struct Biol
Hoofdauteurs: Worden, Evan J., Wolberger, Cynthia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888998/
https://ncbi.nlm.nih.gov/pubmed/31229920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.05.009
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