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Activation and regulation of H2B-Ubiquitin-dependent histone methyltransferases
Covalent modifications of histone proteins regulate a wide variety of cellular processes. Methylation of histone H3K79 and H3K4 is associated with active transcription and is catalyzed by Dot1L and Set1, respectively. Both Dot1L and Set1 are activated by prior ubiquitination of histone H2B on K120 i...
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| Veröffentlicht in: | Curr Opin Struct Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6888998/ https://ncbi.nlm.nih.gov/pubmed/31229920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.05.009 |
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