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Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome
Methylation of histone H3K4 is a hallmark of actively transcribed genes that depends on mono-ubiquitination of histone H2B (H2B-Ub). H3K4 methylation in yeast is catalyzed by Set1, the methyltransferase subunit of COMPASS. We report here the cryo-EM structure of a six-protein core COMPASS subcomplex...
Shranjeno v:
| izdano v: | eLife |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications, Ltd
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7039682/ https://ncbi.nlm.nih.gov/pubmed/31922488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53199 |
| Oznake: |
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