The Oncogenic Polycomb Histone Methyltransferase EZH2 Methylates Lysine 120 on Histone H2B and Competes Ubiquitination

The histone methyltransferase enhancer of zeste 2 (EZH2) is known to be a polycomb protein homologous to Drosophila enhancer of zeste and catalyzes the addition of methyl groups to histone H3 at lysine 27 (H3K27). We previously reported that EZH2 was overexpressed in various types of cancer and play...

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Detalhes bibliográficos
Main Authors: Kogure, Masaharu, Takawa, Masashi, Saloura, Vassiliki, Sone, Kenbun, Piao, Lianhua, Ueda, Koji, Ibrahim, Reem, Tsunoda, Tatsuhiko, Sugiyama, Masanori, Atomi, Yutaka, Nakamura, Yusuke, Hamamoto, Ryuji
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858897/
https://ncbi.nlm.nih.gov/pubmed/24339737
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