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Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins

We previously reported that the histone lysine methyltransferase SUV39H2, which is overexpressed in various types of human cancer, plays a critical role in the DNA repair after double strand breakage, and possesses oncogenic activity. Although its biological significance in tumorigenesis has been el...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Piao, Lianhua, Nakakido, Makoto, Suzuki, Takehiro, Dohmae, Naoshi, Nakamura, Yusuke, Hamamoto, Ryuji
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008405/
https://ncbi.nlm.nih.gov/pubmed/26988914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8072
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