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Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN()()

Phosphatase and tensin homologue (PTEN), one of the well-characterized tumor suppressor proteins, counteracts the phosphatidylinositol 3-kinase-AKT pathway through its unique lipid phosphatase activity. The functions of PTEN are regulated by a variety of posttranslational modifications such as acety...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Nakakido, Makoto, Deng, Zhenzhong, Suzuki, Takehiro, Dohmae, Naoshi, Nakamura, Yusuke, Hamamoto, Ryuji
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415136/
https://ncbi.nlm.nih.gov/pubmed/25925379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2015.03.002
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