The Oncogenic Polycomb Histone Methyltransferase EZH2 Methylates Lysine 120 on Histone H2B and Competes Ubiquitination

The histone methyltransferase enhancer of zeste 2 (EZH2) is known to be a polycomb protein homologous to Drosophila enhancer of zeste and catalyzes the addition of methyl groups to histone H3 at lysine 27 (H3K27). We previously reported that EZH2 was overexpressed in various types of cancer and play...

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Bibliographische Detailangaben
Hauptverfasser: Kogure, Masaharu, Takawa, Masashi, Saloura, Vassiliki, Sone, Kenbun, Piao, Lianhua, Ueda, Koji, Ibrahim, Reem, Tsunoda, Tatsuhiko, Sugiyama, Masanori, Atomi, Yutaka, Nakamura, Yusuke, Hamamoto, Ryuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858897/
https://ncbi.nlm.nih.gov/pubmed/24339737
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