The histone methyltransferase WHSC1 is regulated by EZH2 and is important for ovarian clear cell carcinoma cell proliferation

BACKGROUND: Wolf-Hirschhorn syndrome candidate gene-1 (WHSC1), a histone methyltransferase, has been found to be upregulated and its expression to be correlated with expression of enhancer of zeste homolog 2 (EZH2) in several cancers. In this study, we evaluated the role of WHSC1 and its therapeutic...

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Vydáno v:BMC Cancer
Hlavní autoři: Kojima, Machiko, Sone, Kenbun, Oda, Katsutoshi, Hamamoto, Ryuji, Kaneko, Syuzo, Oki, Shinya, Kukita, Asako, Machino, Hidenori, Honjoh, Harunori, Kawata, Yoshiko, Kashiyama, Tomoko, Asada, Kayo, Tanikawa, Michihiro, Mori-Uchino, Mayuyo, Tsuruga, Tetsushi, Nagasaka, Kazunori, Matsumoto, Yoko, Wada-Hiraike, Osamu, Osuga, Yutaka, Fujii, Tomoyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521555/
https://ncbi.nlm.nih.gov/pubmed/31092221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5638-9
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