Folic acid supplementation reduces multigenerational sperm miRNA perturbation induced by in utero environmental contaminant exposure

Persistent organic pollutants (POPs) can induce epigenetic changes in the paternal germline. Here, we report that folic acid (FA) supplementation mitigates sperm miRNA profiles transgenerationally following in utero paternal exposure to POPs in a rat model. Pregnant founder dams were exposed to an e...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Environ Epigenet
मुख्य लेखकों: Herst, P M, Dalvai, M, Lessard, M, Charest, P L, Navarro, P, Joly-Beauparlant, C, Droit, A, Trasler, J M, Kimmins, S, MacFarlane, A J, Benoit-Biancamano, M-O, Bailey, J L
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2019
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911352/
https://ncbi.nlm.nih.gov/pubmed/31853372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eep/dvz024
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