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Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation

STUDY QUESTION: Do paternal exposures to folic acid deficient (FD), and/or folic acid supplemented (FS) diets, throughout germ cell development adversely affect male germ cells and consequently offspring health outcomes? SUMMARY ANSWER: Male mice exposed over their lifetimes to both FD and FS diets...

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Detalhes bibliográficos
Publicado no:Mol Hum Reprod
Main Authors: Ly, Lundi, Chan, Donovan, Aarabi, Mahmoud, Landry, Mylène, Behan, Nathalie A, MacFarlane, Amanda J, Trasler, Jacquetta
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909862/
https://ncbi.nlm.nih.gov/pubmed/28535307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gax029
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