Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation

STUDY QUESTION: Do paternal exposures to folic acid deficient (FD), and/or folic acid supplemented (FS) diets, throughout germ cell development adversely affect male germ cells and consequently offspring health outcomes? SUMMARY ANSWER: Male mice exposed over their lifetimes to both FD and FS diets...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Hum Reprod
Main Authors: Ly, Lundi, Chan, Donovan, Aarabi, Mahmoud, Landry, Mylène, Behan, Nathalie A, MacFarlane, Amanda J, Trasler, Jacquetta
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909862/
https://ncbi.nlm.nih.gov/pubmed/28535307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gax029
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