Prenatal Exposure to Environmentally-Relevant Contaminants Perturbs Male Reproductive Parameters Across Multiple Generations that are Partially Protected by Folic Acid Supplementation

The paternal environment is thought to influence sperm quality and future progeny may also be impacted. We hypothesized that prenatal exposure to environmentally-relevant contaminants impairs male reproduction, altering embryo gene expression over multiple generations. Folic acid (FA) can improve sp...

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Udgivet i:Sci Rep
Main Authors: Lessard, Maryse, Herst, Pauline M., Charest, Phanie L., Navarro, Pauline, Joly-Beauparlant, Charles, Droit, Arnaud, Kimmins, Sarah, Trasler, Jacquetta, Benoit-Biancamano, Marie-Odile, MacFarlane, Amanda J., Dalvai, Mathieu, Bailey, Janice L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761122/
https://ncbi.nlm.nih.gov/pubmed/31554827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50060-z
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