Stability of the human sperm DNA methylome to folic acid fortification and short-term supplementation

STUDY QUESTION: Do short-term and long-term exposures to low-dose folic acid supplementation alter DNA methylation in sperm? SUMMARY ANSWER: No alterations in sperm DNA methylation patterns were found following the administration of low-dose folic acid supplements of 400 μg/day for 90 days (short-te...

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Bibliografiske detaljer
Udgivet i:Hum Reprod
Main Authors: Chan, D., McGraw, S., Klein, K., Wallock, L.M., Konermann, C., Plass, C., Chan, P., Robaire, B., Jacob, R.A., Greenwood, C.M.T., Trasler, J.M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260859/
https://ncbi.nlm.nih.gov/pubmed/27994001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dew308
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