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SGLT2 inhibition slows tumor growth in mice by reversing hyperinsulinemia

BACKGROUND: Obesity confers an increased risk and accelerates the progression of multiple tumor types in rodents and humans, including both breast and colon cancer. Because sustained weight loss is rarely achieved, therapeutic approaches to slow or prevent obesity-associated cancer development have...

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Publicat a:Cancer Metab
Autors principals: Nasiri, Ali R., Rodrigues, Marcos R., Li, Zongyu, Leitner, Brooks P., Perry, Rachel J.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907191/
https://ncbi.nlm.nih.gov/pubmed/31867105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-019-0203-1
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