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SGLT2 inhibition slows tumor growth in mice by reversing hyperinsulinemia

BACKGROUND: Obesity confers an increased risk and accelerates the progression of multiple tumor types in rodents and humans, including both breast and colon cancer. Because sustained weight loss is rarely achieved, therapeutic approaches to slow or prevent obesity-associated cancer development have...

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Bibliografische gegevens
Gepubliceerd in:Cancer Metab
Hoofdauteurs: Nasiri, Ali R., Rodrigues, Marcos R., Li, Zongyu, Leitner, Brooks P., Perry, Rachel J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907191/
https://ncbi.nlm.nih.gov/pubmed/31867105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-019-0203-1
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