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Growth-inhibiting conditions slow growth plate senescence

The mammalian growth plate undergoes programed senescence during juvenile life, causing skeletal growth to slow with age. We previously found that hypothyroidism in rats slowed both growth plate chondrocyte proliferation and growth plate senescence, suggesting that senescence is not dependent on age...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Endocrinol
Prif Awduron: Forcinito, Patricia, Andrade, Anenisia C, Finkielstain, Gabriela P, Baron, Jeffrey, Nilsson, Ola, Lui, Julian C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289067/
https://ncbi.nlm.nih.gov/pubmed/20974641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-10-0302
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