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Growth-inhibiting conditions slow growth plate senescence

The mammalian growth plate undergoes programed senescence during juvenile life, causing skeletal growth to slow with age. We previously found that hypothyroidism in rats slowed both growth plate chondrocyte proliferation and growth plate senescence, suggesting that senescence is not dependent on age...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Endocrinol
Hauptverfasser: Forcinito, Patricia, Andrade, Anenisia C, Finkielstain, Gabriela P, Baron, Jeffrey, Nilsson, Ola, Lui, Julian C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289067/
https://ncbi.nlm.nih.gov/pubmed/20974641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-10-0302
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