Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats

It has been demonstrated that the K(+)-dependent Na(+)/Ca(2+) exchanger, NCKX2, is a new promising stroke neuroprotective target. However, because no pharmacological activator of NCKX2 is still available, microRNA (miRNA) may represent an alternative method to modulate NCKX2 expression. In particula...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther Nucleic Acids
Egile Nagusiak: Cuomo, Ornella, Cepparulo, Pasquale, Anzilotti, Serenella, Serani, Angelo, Sirabella, Rossana, Brancaccio, Paola, Guida, Natascia, Valsecchi, Valeria, Vinciguerra, Antonio, Molinaro, Pasquale, Formisano, Luigi, Annunziato, Lucio, Pignataro, Giuseppe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Gene & Cell Therapy 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906731/
https://ncbi.nlm.nih.gov/pubmed/31791013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.10.022
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