miR-206 Reduces the Severity of Motor Neuron Degeneration in the Facial Nuclei of the Brainstem in a Mouse Model of SMA

Spinal muscular atrophy (SMA) is a severe neuromuscular disease affecting infants caused by alterations of the survival motor neuron gene, which results in progressive degeneration of motor neurons (MNs). Although an effective treatment for SMA patients has been recently developed, the molecular pat...

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Vydáno v:Mol Ther
Hlavní autoři: Valsecchi, Valeria, Anzilotti, Serenella, Serani, Angelo, Laudati, Giusy, Brancaccio, Paola, Guida, Natascia, Cuomo, Ornella, Pignataro, Giuseppe, Annunziato, Lucio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132835/
https://ncbi.nlm.nih.gov/pubmed/32075715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.01.013
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