Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats

It has been demonstrated that the K(+)-dependent Na(+)/Ca(2+) exchanger, NCKX2, is a new promising stroke neuroprotective target. However, because no pharmacological activator of NCKX2 is still available, microRNA (miRNA) may represent an alternative method to modulate NCKX2 expression. In particula...

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Publicat a:Mol Ther Nucleic Acids
Autors principals: Cuomo, Ornella, Cepparulo, Pasquale, Anzilotti, Serenella, Serani, Angelo, Sirabella, Rossana, Brancaccio, Paola, Guida, Natascia, Valsecchi, Valeria, Vinciguerra, Antonio, Molinaro, Pasquale, Formisano, Luigi, Annunziato, Lucio, Pignataro, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906731/
https://ncbi.nlm.nih.gov/pubmed/31791013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.10.022
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