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PINK1 phosphorylates ubiquitin predominantly in astrocytes
Loss-of-function mutations in PINK1 are causally linked to recessively inherited Parkinson’s disease (PD), with marked loss of dopaminergic neurons in the substantia nigra that are required for normal movement. PINK1 is a nuclear-encoded mitochondrial-targeted kinase that phosphorylates a conserved...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | NPJ Parkinsons Dis |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group UK
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6906478/ https://ncbi.nlm.nih.gov/pubmed/31840043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41531-019-0101-9 |
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