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Enhanced susceptibility of PINK1 knockout rats to α-synuclein fibrils

The main neuropathological hallmarks of Parkinson’s disease (PD) are loss of dopaminergic neurons in the substantia nigra and intraneuronal protein aggregates immunoreactive for α-synuclein phosphorylated at serine 129 (pS129). Most cases of PD are idiopathic; however, genetic mutations have been id...

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Détails bibliographiques
Publié dans:Neuroscience
Auteurs principaux: Creed, Rose B., Goldberg, Matthew S.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510511/
https://ncbi.nlm.nih.gov/pubmed/32353461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2020.04.032
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