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Pink1 interacts with α-synuclein and abrogates α-synuclein-induced neurotoxicity by activating autophagy
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases, characterized by degeneration of dopaminergic neurons in the substantia nigra. α-synuclein (α-syn) and PTEN-induced putative kinase (PINK)1 are two critical proteins associated with the pathogenesis of PD. α-syn induces m...
Shranjeno v:
| izdano v: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5636973/ https://ncbi.nlm.nih.gov/pubmed/28933786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.427 |
| Oznake: |
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